How I treat How I treat idiopathic thrombocytopenic purpura (ITP)

نویسندگان

  • Douglas B. Cines
  • James B. Bussel
چکیده

Our goal is to set forth our opinion of the best approach to managing adults with primary idiopathic (autoimmune) thrombocytopenic purpura (ITP), with emphasis on the word “opinion.” The paucity of evidence-based medicine on this topic has been noted.1 Both the American Society of Hematology2 and the British Committee for Standards in Haematology General Haematology Task Force3 have issued “practice guidelines.” These, in large part, proved to be compendia of opinions from panels of experienced physicians who concurred on some matters but not on others. We cite published evidence where we find it compelling and reproducible, but much of what follows rests on our mutual experience treating patients, both onand off-study, rather than an encyclopedic, heavily referenced review. Many issues remain unresolved, expert opinions differ for good reason, and it is likely that our own approach will change based on emerging data. Comprehensive reviews on pathogenesis, laboratory testing, secondary ITP, ITP in children, and treatment are to be found elsewhere.4,5

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تاریخ انتشار 2005